Pivaloyl chloride CAS #3282-30-2

Trimethylacetyl chloride is used as a precursor in the preparation of tert-butyl peroxypivalate, guttiferon A derivatives, which is potential for the treatment of malaria. It is used as a raw material in the production of synthetic acidamide medicament and phenol ester medicament. In addition to this, it is used for the synthesis of active pharmaceutical ingredients such as aminobenzylpenicilin, cephalexin, cefazolin, dipivefrin and dipivalyl epinephrine. It is also used in heavy polymerization, N-acylating agent for amines, Schiff bases, pyrrolidinones as well as an O-acylating agent for alcohols, lactones and saccharides.

Pivaloyl chloride CAS #3282-30-2

Pivaloyl chloride Basic information
Product Name: Pivaloyl chloride
Synonyms: 2,2-dimethyl-propanoylchlorid;Acetyl chloride, trimethyl-;Neopantanoyl chloride;PIVALOYL CHLORIDE(PVCL);Pivaloyl chloride(Trimethylacetyl chloride);Primethylacetyl chloride;Pivalpyl chloride;Pivaloyl chlorode
CAS: 3282-30-2
MF: C5H9ClO
MW: 120.58
EINECS: 221-921-6
Product Categories: Agrochemical Intermediates;Acid Halides;Building Blocks;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;K00001
Mol File: 3282-30-2.mol
Pivaloyl chloride Structure
Pivaloyl chloride Chemical Properties
Melting point -56 °C
Boiling point 105-106 °C(lit.)
density 0.980 g/mL at 20 °C
vapor density >1 (vs air)
vapor pressure 36 mm Hg ( 20 °C)
refractive index n20/D 1.412(lit.)
Fp 48 °F
storage temp. Store below +30°C.
solubility Miscible with acetonitrile.
form Liquid
color Clear almost colorless to light pink
explosive limit 1.9-7.4%(V)
Water Solubility Hydrolysis
Sensitive Moisture Sensitive
BRN 385668
Stability: Hygroscopic, Moisture Sensitive, Volatile
InChIKey JVSFQJZRHXAUGT-UHFFFAOYSA-N
LogP 1.680 (est)
CAS DataBase Reference 3282-30-2(CAS DataBase Reference)
NIST Chemistry Reference Propanoyl chloride, 2,2-dimethyl-(3282-30-2)
EPA Substance Registry System Propanoyl chloride, 2,2-dimethyl- (3282-30-2)
Safety Information
Hazard Codes F,T+,T
Risk Statements 11-14-22-26-34-23
Safety Statements 16-26-36/37/39-45-38-28A
RIDADR UN 2438 6.1/PG 1
WGK Germany 1
F 9-19
TSCA Yes
HazardClass 6.1
PackingGroup I
HS Code 29159080

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