Evans Blue CAS# 314-13-6

Evans Blue is a blue crystal with a green metallic luster. It is very soluble in water, slightly soluble in ethanol, and almost insoluble in benzene, chloroform, and ether. It is soluble in acids and alkalis. It is hygroscopic, inducing moisture. It changes color when the pH is close to 10.
Evans Blue is used for estimation of blood volume and in double-labeling procedure for studying axonal branching. It acts as an inhibitor of L-glutamate and kainate receptor-mediated currents. It is also a P2X-selective purinoceptor antagonist. It is also useful in molecular biology.

Evans Blue CAS# 314-13-6

Product Name: Evans Blue
Synonyms: EVANS BLUE C.I. No 23860;EvansBlue,99%;DiazoBlue;1,3-Naphthalenedisulfonic acid, 6,6-(3,3-dimethyl1,1-biphenyl-4,4-diyl)bis(azo)bis4-amino-5-hydroxy-, tetrasodium salt;4,4′-Bis[7-(1-amino-8-hydroxy-2,4-disulfo)naphthylazo]-3,3′-bitolyl tetrasodium salt;6,6′-[(3,3′-Dimethyl-4,4′-biphenylylene)bis(azo)]bis[4-amino-5-hydroxy-1,3-naphthalenedisulfonic acid] tetrasodium salt;6,6′-[(3,3′-Dimethyl[1,1′-biphenyl]-4,4′-diyl)bis(azo)]bis(4-amino-5-hydroxy-1,3-naphthalenedisulfonic acid disodium);3-[[4′-[(4-Amino-2-methyl-5-methoxyphenyl)azo]-3,3′-dimethoxy-1,1′-biphenyl-4-yl]azo]-4-hydroxynaphthalene-1,5-disulfonic acid disodium salt
CAS: 314-13-6
MF: C34H29N6NaO14S4
MW: 896.86
EINECS: 206-242-5
Product Categories: MATULANE;Biological Dye;Glutamate receptor;Organics
Mol File: 314-13-6.mol
Evans Blue Structure
Evans Blue Chemical Properties
storage temp. Store at RT.
solubility DMSO (Slightly), Water (Slightly)
Colour Index 23860
form Powder/Solid
color Dark Brown
Water Solubility 280 g/L (20 ºC)
Merck 14,3905
Stability: Stable. Incompatible with strong reducing agents, strong oxidizing agents.
CAS DataBase Reference 314-13-6
IARC 3 (Vol. 8, Sup 7) 1987
EPA Substance Registry System C.I. Direct Blue 53 (314-13-6)
Safety Information
Hazard Codes T,F
Risk Statements 45-63-11-61-20/21/22
Safety Statements 53-45-36/37-16-36/37/39
WGK Germany 3
RTECS QJ6440000
TSCA Yes
HS Code 32129000
Toxicity LD50 intraperitoneal in mouse: 340mg/kg

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