Erythrosin B CAS#15905-32-5

Erythrosin B, also called as eosin B, is a xanthene dye. It belongs to the family of fluorescein dyes. It plays a major role in inhibiting dopamine uptake and high affinity 3H-ouabain binding and ion transport in synaptosomes from rat caudate nucleus.
Erythrosin B is used as a red coloring in some foods such as cherries and fish. It is used as printing ink, dental plaque disclosing agent and biological stain. It finds application as a radiopaque medium and sensitizer for orthochromatic photographic films. It is utilized as a cake-decorating gel. In addition to this, it is used in sweets such as candies and popsicles.

Erythrosin B CAS#15905-32-5

Product Name: ERYTHROSIN B
Synonyms: 2’,4’,5’,7’-tetraiodo-fluorescei;2’,4’,5’,7’-tetraiodofluorescein;3’,6’-Dihydroxy-2’,4’,5’,7’-tetraiodospiro[iso-benzofuran-1(3H),9’-[9H]xanthen]-3-onedisodiumsalt;9’-(9h)xanthen)-3-one,3’,6’-dihydroxy-2’,4’,5’,7’-spiro(isobenzofuran-1(3h;9’-[9H]xanthen]-3-one,3’,6’-dihydroxy-2’,4’,5’,7’-tetraiodo-Spiro[isobenzofuran-1(3H);erythrosineacid;iodeosin;Erythrosin B, spirit soluble, pure, 95%
CAS: 15905-32-5
MF: C20H8I4O5
MW: 835.89
EINECS: 240-046-0
Product Categories: Inhibitors;Organics
Mol File: 15905-32-5.mol
ERYTHROSIN B Structure
ERYTHROSIN B Chemical Properties
Melting point 303 °C (dec.)(lit.)
Boiling point 628.3±55.0 °C(Predicted)
density 2.4391 (estimate)
storage temp. room temp
solubility spirit: soluble
form powder
Colour Index 45430:2
pka 7.21±0.20(Predicted)
color Red
Water Solubility Soluble in water, spirit, methanol, methyl cellosolve and ethanol.
EPA Substance Registry System 2′,4′,5′,7′-Tetraiodofluorescein (15905-32-5)
Safety Information
Safety Statements 22-24/25
WGK Germany 2
RTECS LM5940000
TSCA Yes
HS Code 29329990
Toxicity A food color formerly approved for use in the United States and Europe. It was used primarily in jams and marmalades, maraschino cherries, pickles and relishes, etc. The LD50 in rats is 150 mg/kg, i.p., and 600 mg/kg, p.o. Erythrosine has a variety of actions in vitro due in large measure to its ability to affect biological membranes and lipophilic sites of enzymes. Such data have led to the hypothesis that erythrosine could be neurotoxic, but both clinical and preclinical data have suggested that erythrosine is not likely to be neurotoxic at doses that might be encountered. Two other toxicological issues have been raised with this food color. It has been suggested to be a potential, if weak, carcinogen, and it may also contribute to potential thyroid toxicity resulting from release of iodine.

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